姓 名：刘长辉，教授、博士、硕士生导师，十四五应用特色学科带头人，湖南省青年骨干教师，益阳市首批高层次人才、益阳市首批银城托举人才。

招收硕士生学科专业：化学、化学工程与技术、材料与化工

主要研究方向：化学与生物传感研究

教学科研情况：

先后获得国家自然科学面上项目1项，湖南省自然科学基金、湖南省科技计划研究项目等6项资助，在Analysis Chemistry,Journal of Agricultural and Food Chemistry, Angewandte Chemie International Edition,中国科学-化学等期刊发表SCI论文40余篇，获湖南省自然科学奖二等奖1项，湖南省科技进步奖三等奖2项，以第一发明人授权中国发明专利2项。

主持项目

1. 国家自然科学基金面上项目, 21675042,近红外发射双光子荧光纳米探针的设计、合成及其肿瘤分子成像分析, 2017/01-2020/12,主持.

2. 湖南省自然科学基金面上项目, 2018JJ2017,可逆激活型近红外纳米荧光探针的构建及其生物成像研究, 2018/01-2020/12,主持

   发表论文

   (1)Huan Peng,Suna Kong,Xia Deng,Qirong Deng,Fengpei Qi,Changhui Liu*,Ruiren Tang*.Development of a ratiometric fluorescent probe with zero cross-talk for detection of SO₂derivatives in foods and live cells.Journal of Agricultural and Food Chemistry, 2023, 71(39): 14322-14329.

   (2) YiBo Zhou, Zhengxuan Gu,Changhui Liu, Sheng Yang, Xiaofei Ma, Qiaoshu Chen, Yanli Lei, Ke Quan, Juewen Liu, Zhihe Qing*, Ronghua Yang*. A polymeric nanobeacon for monitoring the fluctuation of hydrogen polysulfides during fertilization and embryonic development. Angewandte Chemie International Edition, 2022, 61(16): e202114504.

   (3) Nan Wang, Jianke Su, Qirong Deng, Aijuan Liu, Fengpei Qi, Jin Zhang, Liping Long, Suna Kong,Changhui Liu*, Ruiren Tang*. G-quadruplex-lighted EVCP for the construction of ratiometric fluorescent sensors: detection of hydrogen peroxide and oxidase substrate, Dyes and Pigments, 2020, 177: 108132.

   (4)刘长辉,李银辉,齐风佩,龙立平,杨荣华*.近红外双发射荧光探针比率检测高/半胱氨酸,中国科学-化学, 2017, 47: 1015-1021.

   (5)Changhui Liu, Weiju Chen, Zhihe Qing, Jing Zheng, Yue Xiao, Sheng Yang, Lili Wang, Yinhui Li, Ronghua Yang*. In vivo lighted fluorescence via Fenton reaction: approach for imaging of hydrogen peroxide in living systems, Analytical Chemistry, 2016, 88, 3998-4003.

   (6)Changhui Liu, Zheng Jing, Deng Li, Ma Cheng, Li Jishan, Li Yinhui, Yang Sheng, Yang Jinfeng, Wang Jing, Yang Ronghua*. Targeted intracellular controlled drug delivery and tumor therapy through in situ forming Ag Nanogates on mesoporous silica nanocontainers,ACS Applied Material & Interfaces, 2015, 7(22), 11930-11938.

授权国家发明专利

1. 刘长辉,王贞睿,齐风佩,曹一鸣,罗苗,肖刘平.一种黑茶抗氧化活性的荧光分析方法,国家发明专利, ZL 2018 1 0692139.5, 2020.

2. 刘长辉,李月,银一笑,董艳,赵芝慧,齐风佩,彭欢.一种快速检测碘离子的近红外荧光分析方法,国家发明专利, ZL 2022 1 0327315.1, 2025.

   成果奖励

   (1)刘长辉,李银辉,齐风佩,文富彬,杨金凤.基于生化传感的荧光分析方法学构建,湖南省自然科学奖二等奖,2021.

   联系方式：lchphd@126.com