钟明

职称：教授

性别：男

职务：

办公电话：07308640122

移动电话：13873013201

家庭电话：

家庭住址：

电子邮箱：zhongming2613@163.com

工作学习经历

主讲课程

《制药工艺学》《制药分离技术》《化学教学伦》

研究方向

1.天然药物活性成分分离技术：主要从事植物中生物碱的分离分析及产业化研究

2.化学教学论：主要从事计算机辅助化学教学

主要学术成果

主持国家自然科学基金面上项目1项，湖南省自然科学基金面上项目1项，其它省级项目5项。发表第一作者（含通讯作者）论文30余篇，其中SCI收录论文20余篇。申请并授权专利5项。

承担项目：

1、国家自然科学基金面上项目：表面分子印迹磁性聚合物微球浮选分离苯并菲啶类生物碱. [项目批准号：21276071], 起止时间：2013-2016；

2、湖南省自然科学基金面上项目： 磁性-温敏双重响应水凝胶系统的构建及其双效协同治疗，[项目批准号：2019JJ40101], 起止时间：2018-2021；

3、湖南省科技计划项目：别隐品碱抗肝纤维化药物开发[项目批准号：2009WK3005],已结题；

4、湖南省科技计划项目：分子印迹微球浮选分离抗癌生物碱，批准号：2013FJ3007；

5、湖南省教育厅一般项目：血清指纹图谱在中药复方活性成分研究中的应用，项目批准号：06C372，已结题；

6、湖南省教育厅开放基金：杀钉螺生物碱的高效分离及其与螺类钥孔虫戚血蓝蛋白分子作用机制研究[项目批准号：15K050],已结题；

7、2013年岳阳市产学研结合专项：磁性微球材料的制备及其分离生物碱研究；

8、2017年主持湖南省十三五教育规划课题：构建化工仿真实验教学体系的理论与实践研究(XJK17BGD031)

9、主持湖南省新工科项目：《新工科视域下地方高校化工类专业面向产业变革的协同育人机制创新与实践》

代表性论文：

[1] Ming Zhong, Ke-long Huang^(*), Jian-guo Zeng, Shuang Li, Jin-ming She, Li Zhang, Optimization of Microwave-Assisted Extraction of Protopine and Allocryptopine from Stems of Macleaya cordata (Willd)R. Br. Using Response Surface Methodology[J], Journal of Separation Science, 2010, 33, 2160–2167.(SCI收录)

[2] Zhong Ming, Huang Ke-long^(*), Zeng Jian-guo Li Shuang.Determination of the contents of eight alkaloids in fruits of Macleaya cordata (Willd) R. Br. from different habitats and antioxidant activities of the extracts[J]，Journal of Central South University of Technology, 2010, 17(3): 472−479. (SCI、EI收录)

[3] Zhong Ming, Huang Ke-long^(*), Zeng Jian-guo, Li Shuang, She Jin-ming, Li Gui-yin. Evaluation of molluscicidal activities of benzo[c]phenanthridine alkaloids from Macleaya cordata (Willd) R. Br. on snail hosts of Schistosoma japonicum[J], Journal of medicinal plants research,2011，5(4):521–526 .(SCI收录)

[4]M. Zhong^(*), R. Q. Long, Y. H. Wang and C. L. Chen. Interaction of Chelerythrine with Keyhole Limpet Hemocyanin: a Fluorescence Spectroscopy and Molecular Docking Study, Journal of Applied Spectroscopy, 2018, 85(2): 320-323. (SCI收录)

[5]Ming Zhong^(*), Yan-Hong Wang, Lu Wang, Rui-Qing Long, Chun-Lin Chen^(*)..Synthesis and characterization of magnetic molecularly imprinted polymers for enrichment of sanguinarine from the extraction wastewater of M. cordata. Journal of Industrial and Engineering Chemistry, 2018，66(25):107-115. (SCI收录)

[6]Ming Zhong^(*), Yan-Hong Wang, Lu Wang, Rui-Qing Long, Chun-Lin Chen^(*). Preparation and application of magnetic molecularly imprinted polymers for the isolation of chelerythrine from Macleaya cordata. Journal of Separation Science, 2018,41(16): 3318-3327 (SCI收录)

[7]Lu Wang,Yanhong Wang,Binbin Zhou^*, Ming Zhong^*. Synthesis and characterization of core‐shell magnetic molecularly imprinted polymers for selective extraction of allocryptopine from the wastewater of Macleaya cordata (Willd) R. Br., Journal of Molecular Recognition, 2020, 33(8): e2844.(SCI收录)  

[8]Yan-hong Wang,Ming Zhong^*,Lu Wang,Yu-liang Liu,Bin Wang^*,Yong Li.Chelerythrine loaded composite magnetic thermosensitive hydrogels as a novel anticancer drug-delivery system, Journal of Drug Delivery Science and Technology,2019, 54: 101293.   (SCI收录)  

[9]BinbinZhou,LuWang,JihongZhang,YuliangLiu,MingZhong（*）.Inhibition of aggregation and toxicity of a-synuclein in the presence of copper by an N-methylated peptide.JOURNAL OF MOLECULAR STRUCTURE,2020,1211:1-8.(SCI收录)

[10] Meng Liang,Lijun Huang,Xinyi Li, Xiaoqi Zheng,Suhao Fan,Ming Zhong* ,Binbin

Zhou. Microchemical Journal. 2025, 213 (3) :113903-113913. (SCI收录)

[11] Yu, Linyan, Wu, Xiongwei, Liu, Qi, Liu, Liangliang, Jiang, Xinyu, Yu, Jingang^(*), Feng, Chen，Zhong, Ming^(*). Removal of Phenols from Aqueous Solutions by Graphene Oxide Nanosheet Suspensions，Journal of Nanoscience and Nanotechnology, 16(12): 12426~12432. 2016(SCI收录)

[12] Jie Teng, Xiang Zeng, Xiu-Hui Zhao, Zhi-Hang Wang, Jin-Gang Yu^(*), Xuan-Ming Xu, Ming Zhong^(*), Xiong-Wei Wu. Dibromocarbene Modified Graphene: Preparation, Characterization and Its Application in Removal of Pb(II) from Aqueous Solutions, Nanoscience and Nanotechnology Letters, 8(3): 226~231. 2016(SCI收录)

[13] Cuimei Chen, Ming Zhong, Guiyin Li, Fei Yang, Ruixue Huang, Wen Xiao, Ping Ding^(*). Optimization on preparation conditions of calcium-crosslinked modified chitosan as potential matrix material for theophylline sustained-release beads and its evaluation of release kinetics, Journal of Alloys and Compounds, 658(10): 348~355. 2016(SCI收录)

[14] Jin-Gang Yu, Bao-Yu Yue, Xiong-Wei Wu, Qi Liu, Xin-Yu Jiang, Ming Zhong^(*), Hui-Yong Li, Shan-Shan Li. The Covalently Organic Functionalization of Graphene: Methodologies and Protocols, Current Organic Chemistry, 2016, 20(12): 1284~1298. (SCI收录)

[15] Hui-Yong Li, Bao-Yu Yue, Jin-Gang Yu, Xiong-Wei Wu, Wen-Xin Zhou, Nan Zhou, Jie Teng, Ming Zhong^(*). Diiodocarbene Modified Graphene: Preparation, Characterization and Its Application as a Novel Adsorbent for Aqueous Removal of Pb(II), Nanoscience and Nanotechnology Letters, 8(5): 387~392. 2016(SCI收录)

[16]Guo-Xiang Wang^(*), Jie-Yu He, Li-Chao Liu, Hu Wu, Ming Zhong. Photo-induced atom transfer radical polymerization of MMA with chlorophll A as photoinitiator, Journal of polymer research, 23(5): 1-5. 2016(SCI收录)

[17] Zhi-Hang Wang, Bao-Yu Yue, Jie Teng, Fei-Peng Jiao, Xin-Yu Jiang, Jin-Gang Yu^(*), Ming Zhong, Xiao-Qing Chen. Tartaric acid modified graphene oxide as a novel adsorbent for high-efficiently removal of Cu(II) and Pb(II) from aqueous solutions, Journal of the Taiwan Institute of Chemical Engineers, 66: 181~190. 2016 (SCI收录)

[18] Binbin Zhou,Xinyi Li,Hao Xie,Xingxin Sheng,Lijun Huang,Yongbo Zhu,Meng Liang,Ming Zhong*.Construction of an electrochemical sensor based on magnetic molecularly imprinted polymer‑zeolite imidazole framework‑8 for detection of 3,4‑benzopyrene. Microchimica Acta (2025) 192:14 https://doi.org/10.1007/s00604-024-06858-4. (SCI收录)

[19] Lijun Huang, Yuliang Liu, Xingxin Sheng,Yongbo Zhu, Xinyi Li,Meng Liang, Hao Xie，

Ming Zhong *,Binbin Zhou. Fabrication of a MIP-CuMOFs@SA-CS electrochemical sensor based on CuHCF for the highly selective detection of chelerythrine. Microchemical Journal.

2025,209(6) :112743-112751.(SCI收录)

[20] Bin-Hong He, Jieyu He, Guo-Xiang Wang^(*), Hu Wu, Ming Zhong. Photo-induced controlled/living copolymerization of styrene and acrylic acid and determination of reactivity ratios, Iranian Polymer Journal, 23: 819~826. 2014(SCI收录)

[21]Jia-Ying Yang, Bao-Yu Yue, Jie-Teng*, Qi Liu*, Xin-Yu Jiang, Ming Zhong*, Fang-Liang Zhou, Jin-Gang Yu*. Dichlorocarbene modified graphene oxide nanocomposite fabricated by a facile hydrothermal method and its adsorption properties toward rare earth elements, Desalination and Water Treatment, 2019, (162): 260–268. (SCI收录)

[22]Jia-Ying Yang, Bao-Yu Yue,Jie-Teng*, Qi Liu*, Xin-Yu Jiang, Ming Zhong*. Fang-Liang Zhou, Jin-Gang Yu*.Dichlorocarbene modified graphene oxide nanocomposite fabricated by a facile hydrothermal method and its adsorption properties toward rare earth elements,Desalination and Water Treatment,2019,162():260-268.doi: 10.5004/dwt.2019.24300(SCI收录)

[23] 钟明, 黄可龙, 曾建国,等.  UPLC-ESI-MS快速测定博落回各器官中主要生物碱的含量.中南大学学报（自然科学版），2011，42（7）：1989-1905.（EI收录）

[24] 钟明，黄可龙，曾建国，等.博落回总生物碱对钉螺生殖腺超微结构的影响研究.中国病原生物学杂志，2009,4(10):758-761.

[25] 钟明,冯务群.制药工程专业《仪器分析》双语教学研究.医学教育探索，2007，6(4):335-336

[26] 钟明,博落回中微量生物碱的研究进展.湖南中医药大学学报, 2007, 27:387-388.

[27] 钟明. 气相色谱法测定工业废水中的低浓度甲醇.化工时刊, 2004, 18(10) : 48-50.

[28] 钟明.气相色谱虚拟实验的开发与应用. 大学化学.2004,19(6):28-30.

[29] 钟明,佘金明,黄宏新. 《有机化学实验》课程教改的新思路——基于VRML的虚拟实验研究与开发. 化学教育.2003, 24(7):54-56.

[30] 钟明, 黄宏新.  虚拟现实技术在化学CAI中的实现方法. 吉林师范大学学报, 2003,24(1):95-97.

[31] 钟明.Origin在色谱实验数据粗大误差分析中的应用.化工技术与开发，2004,33(6):35-37.

[32] 钟明. 毛细管气相色谱法测定面粉中增白剂BPO的含量. 湖南理工学院学报（自然科学版）, 2004年3期

[33] 钟明,冯务群,蒋庆娇 . 博落回生物碱的超声提取动力学模型.湖南理工学院学报（自然科学版）, 2012,25(4):71-74.

[34] 钟明,钱多,彭敏.乙氧基血根碱与人血清白蛋白的相互作用.湖南理工学院学报（自然科学版）, 2013,26(4):35-39.

授权专利：

1、 钟明；冯务群；阎建辉；易健民；唐课文；向阳；血根碱及其盐作为杀精子剂的应用，

2017-9-15，中国，ZL201410004442.3

2、 钟明; 龙睿卿; 王艳红;苯并菲啶类生物碱分子印迹磁性聚合物微球的制备方法及应用，

2019-11-7,中国，ZL201710005800.6

3、 博落回总生物碱或其盐在抗血吸虫致肝纤维化中的应用，授权专利号CN 101297870 B，

排名第二

4、别隐品碱及其盐在抗肝纤维化中的应用，授权专利号CN 101327211 B, 排名第二

5、一种制备高纯度别隐品碱的提取方法，授权专利号CN 101362766 B,排名第二

个人简介

钟明，男，1966年10月生，湖南岳阳人，湖南理工大学化工学院教授，博士，硕士生导师，中共党员。现任湖南省化妆品安全专家，湖南省中小学教师正高级评委。主持国家自然科学基金面上项目1项，湖南省自然科学基金面上项目1项，其它省级项目5项。发表第一作者（含通讯作者）论文40余篇，其中SCI收录论文30篇。申请并授权专利5项。