周彬彬

职称：教授

性别：男

移动电话：19892578868

电子邮箱：12019039@hnist.edu.cn

工作学习经历

主讲课程

《专业英语》《文献检索与论文写作》《表面活性剂化学》《药事管理等》《化妆品学概论》

研究方向

电化学传感器的构建及应用，功能性多肽的设计、合成及应用。

主要学术成果

将电化学检测方法与分子印迹技术相结合，通过碳材料、金属纳米粒子、MOFs等材料的修饰，构建系列电化学传感器，用于食品、环境中有毒有害物质的检测。同时，针对阿尔茨海默病和帕金森病的致病机理，设计、合成潜在多肽药物分子，取得了一些研究成果。迄今已发表包括：Food Chemistry，Biosensors & Bioelectronics, Chemical Engineering Science, Food Chemistry: X, Microchemical Journal在内的SCI论文40余篇。2篇论文入选ESI高被引论文；获中国发明专利授权6项；主编《化妆品学概论》教材1部，以副主编参编《皮肤生理学》教材1部。

承担项目：

1. 湖南省自然科学基金省部联合基金项目（省部级）：面向食品中生物毒素的便携式电化学检测装置的构建及应用（2026JJ80801），5万元，主持，排名第1。

2. 湖南省自然科学基金省部联合基金项目（省部级）：分子印迹电化学传感器的构建及其对食品中有害物质的检测（2023JJ60146），10万元，主持，排名第1。

3. 湖南省教育厅优秀青年基金项目（市厅级）：自组装多肽-磁性水凝胶的设计及其对抗癌药物的控制释放研究（19B236），4万元，主持，排名第1。

4. 湖南省教育厅重点项目（市厅级）：智能分子印迹水凝胶的制备、分子识别及其缓/控释机理研究（19A199），8万元，参与，排名第2。

5. 湖南省自然科学基金青年基金项目（省部级）：多功能纳米药物的设计合成及其在阿尔茨海默病中的应用（2018JJ3300），5万元，主持，排名第1。

6. 湖南省食药监局食品药品安全科技重点项目（市厅级）：自组装短肽-明胶杂化水凝胶对乳糖酶的控释及其在牛奶和乳制品中的应用（湘食药科R201702），10万元，主持，排名第1。

7. 湖南省食药监局食品药品安全科技一般项目（市厅级）：基于可视化分子探针的食品中氰化物快速检测技术研究开发（湘食药科R201516），5万元，主持，排名第1。

8. 湖南省自然科学基金面上项目（省部级）：自组装多肽-明胶杂化水凝胶对乳糖酶的控释研究（2018JJ2232），10万元，参与，排名第2。

9. 湖南省教育厅教学改革项目（省部级）：化妆品专业课程教学中思政元素融入的探索与实践（HNJG-20230858），1.5万元，主持，排名第1。

10. 新化恒睿电子陶瓷科技有限公司委托项目（横向）：多孔氧化铝陶瓷膜支撑体的改性技术研发（JSHT-L-2021-078），100万元，主持，排名第1。

11. 长沙友创陶瓷科技有限公司委托项目（横向）：氧化铝陶瓷粉体改性技术研发（2023430607000），80万元，主持，排名第1。

代表性论文：

1. Binbin Zhou, Xuan Yang , Shan Li , Xiaoqi Zheng , TianYu Zhang , Liang Chen*, An Liu*，A synergistic signal-amplifying electrochemical sensor based on CuMOFs/AgNP/rGNRs nanocomposites for ultra-sensitive detection of tetracycline, Microchemical Journal, 2026, 227, 118635.  DOI: https://doi.org/10.1016/j.microc.2026.118635. （SCI2区）

2. Xuan Yang, Yuan Li, Jing Cao, TianYu Zhang, Xiaoqi Zheng, Liang Chen, Binbin Zhou*, High sensitivity detection of tetracycline using a molecularly imprinted electrochemical sensor based on AgNPs and rGNRs synergistic signal amplification. Microchemical Journal, 2026, 224, 117785.  DOI: https://doi.org/10.1016/j.microc.2026.117785. （SCI2区）

3. Chenxi Xu, Yun Peng, Lanyun Yang, Liang Chen*, Jiale Sun, Shuangshuang Ren, Binbin Zhou*, Zhaohui Hou. Asphalt−derived nitrogen, boron co−doped porous carbon for promoted lithium storage property. Chemical Engineering Science, 2026, 325, 123451. DOI: https://doi.org/10.1016/j.ces.2026.123451. （SCI2区）

4. Binbin Zhou, Xiaoqi Zheng, Yuan Li, Xuan Yang, Xinyi Li, An Liu*, Liang Chen*. Palladium-metallene and polypyrrole molecular imprinted nanotube modified electrochemical sensor for zearalenone detection. Journal of Food Composition and Analysis, 2025, 148, 108179. DOI: https://doi.org/10.1016/j.jfca.2025.108179. （SCI2区）

5. Binbin Zhou, Xinyi Li, Xiaoqi Zheng, Meng Liang, Zitong Yang, An Liu*, Liang Chen*. A self-reporting electrochemical sensor for carbendazim in food based on magnetic molecularly imprinted MOFs. Food Chemisty, 2025, 487, 144789. DOI: org/10.1016/j.foodchem.2025.144789. （SCI1区）

6. Meng Liang, Lijun Huang, Xinyi Li, Xiaoqi Zheng, Suhao Fan, Ming Zhong*, Binbin Zhou*. Construction of a molecularly imprinted electrochemical sensor based on MIP-ZrMOFs/RGO for highly sensitive and selective detection of ketoprofen. Microchemical Journal, 2025, 213, 113903. DOI: org/10.1016/j.microc.2025.113903. （SCI2区）

7. Binbin Zhou, Xinyi Li, Hao Xie, Xingxin Sheng, Lijun Huang, Yongbo Zhu, Meng Liang, Ming Zhong*. Construction of an electrochemical sensor based on magnetic molecularly imprinted polymerzeolite imidazole framework8 for detection of 3,4benzopyrene. Microchimica Acta, 2025, 192, 14.  DOI: org/10.1007/s00604-024-06858-4（SCI2区）

8. Xiaoqi Zheng, Xuan Yang, Hao Xie, Yuan Li, Xinyi Li, Binbin Zhou*. A molecularly imprinted electrochemical sensor based on rGO@rGNR modification for zearalenone determination. Journal of Food Composition and Analysis, 2025, 141, 107361. DOI: org/10.1016 /j.jfca.2025.107361. （SCI2区）

9. Lijun Huang, Yuliang Liu, Xingxin Sheng, Yongbo Zhu, Xinyi Li, Meng Liang, Hao Xie , Ming Zhong* , Binbin Zhou*. Fabrication of a MIP-CuMOFs@SA-CS electrochemical sensor based on CuHCF for the highly selective detection of chelerythrine. Microchemical Journal, 2025, 209, 112743. DOI: org/10.1016/j.microc.2025.112743 （SCI2区）

10. Binbin Zhou, Hao Xie, Xinyi Li, Yongbo Zhu, Lijun Huang, Ming Zhong*, Liang Chen*. Construction of a self–reporting molecularly–imprinted electrochemical sensor basedon CuHCF modified by rGNR–rGO for the detection of zearalenone. Food Chemisty, 2024. 448, 139154. DOI: org/10.1016/j.foodchem.2024.139154. （SCI1区）

11. Binbin Zhou, Xingxin Sheng, Jing Cao, Hao Xie, Xinyi Li, Lijun Huang, Ming Yang*, Ming Zhong*, You-Nian Liu*. A novel electrochemical sensor based on dual-functional MMIP-CuMOFs for both target recognition and signal reporting and its application for sensing bisphenol A in milk, Food Chemistry, 2024, 437, 137756. DOI: org/10.1016/j.foodchem.2023.137756 （SCI1区）

12. Xincheng Hu, Wei Wei, Xinyi Li, Yewen Yang, Binbin Zhou*. Recent advances in ratiometric electrochemical sensors for food analysis. Food Chemistry: X, 2024, 23, 101681. DOI: org/10.1016/j.fochx.2024.101681. （SCI1区）

13. Liang Chen, Yangyang Chen, Liting Zeng, Chenxi Xu*, Xinrui Li, Ying Liu, Jie Ouyang, Jiale Sun, Binbin Zhou*, Zhaohui Hou. Synthesis of 3D FeS embedded into N, S co–doped carbon nanotube/graphene framework for electrochemical application. International Journal of Hydrogen Energy. 2024, 78, 1016–1023. DOI: org/10.1016/j.ijhydene.2024.06.390. （SCI2区）

14. Binbin Zhou, Hao Xie, Sisi Zhou, Xingxin Sheng, Liang Chen*, Ming Zhong*，Construction of AuNPs/reduced graphene nanoribbons co-modified molecularly imprinted electrochemical sensor for the detection of zearalenone，Food Chemistry, 2023, 423, 136294. （SCI1区）

15. Ming Zhong, Lijun Huang, Binbin Zhou*, Yuliang Liu*, Mian Fang, Ying Wang, Rapid Preparation of Magnetic Zinc MOF Molecular Imprinting Polymers and Efficient Pretreatment of Pyrene in Vegetable Oil, Food Analytical Methods, 2023, 16, 1110-1119.（SCI3区）

16. Yuliang Liu, Lijun Huang, Yongbo Zhu, Hao Xie, Ming Zhong*, Binbin Zhou*, Optimal preparation of pyrene magnetic molecularly imprinted polymers by simulation calculation and study of its adsorption properties, Materials Today Communications, 2023, 37, 107327.（SCI3区）

17. Yongbo Zhu, Lijun Huang, Meng Liang, Zuokun Zhang, Hao Xie, Xingxin Sheng, Xinyi Li, Ming Zhong*, Binbin Zhou*, Green synthesis of plate‑shaped CuONPs using Macleaya cordata(Wild.) R.BR extracts for photocatalytic degradation and antibacterial properties, Biomass Conversion and Biorefinery, 2023, 14, 29175–29187（SCI3区）

18. Yongbo Zhu, Meng Liang, Yuliang Liu, Ming Zhong*, Binbin Zhou*, Lijun Huang, Zuokun Zhang, Magnetic Metal-Organic Framework Material Synthesized by Molecular Imprinting Technology for Analysis of Bisphenol A, Chromatographia, 2023, 86, 669–676.（SCI4区）

19. Zuokun Zhang, Sisi Zhou, Xingui Wang, Ruimei Liang, Xingxin Sheng, Yongbo Zhu, Lijun Huang, Binbin Zhou*, Ming Zhong*, Synthesis of pH/ temperature sensitive gelatin/peptide composite hydrogels and its characterization for potential controlled drug release applications, Materials Today Communications, 2023, 36, 106425. （SCI3区）

20. Binbin Zhou, Xingxin Sheng, Hao Xie, Sisi Zhou, Ming Zhong*, Molecularly imprinted electrochemistry sensor based on AuNPs/RGO modification for highly sensitive and selective detection of nitrofurazone, Food Analytical Methods, 2023, 16, 709-720.

21. Ming Yang, Lin sheng Huang, Pei Guo, Binbin Zhou*, Yong Tao*, Changan Yang*, Design, synthesis and performance control of dendritic fluorescent liquid crystal polymers with aggregation-induced emission properties, European Polymer Journal, 2023, 186, 111855.（SCI2区）

22. Binbin Zhou, Xingxin Sheng, Hao Xie, Sisi Zhou, Ming Zhong*, An Liu*, Inhibition of Alzheimer’s Aβ_1-42 Fibrillogenesis and Removal of Copper Ions by Polypeptides Modified Gold Nanoparticles, Chem. Biodivers., 2022, 19, e202200342.（SCI3区）

23. An Liu, Yonggui Zhou, Tian Zhao, Binbin Zhou*, Jia Xu, MiRNA‑3662 reverses the gemcitabine resistance in pancreatic cancer through regulating the tumor metabolism, Cancer Chemotherapy and Pharmacology, 2021, 88, 343-357.

24. Binbin Zhou, Lu wang, Jihong Zhang, Yuliang Liu and Ming Zhong*, Inhibition of aggregation and toxicity of α-synuclein in the presence of copper by an N-methylated peptide, Journal of Molecular Structure，2020, 1211, 128079.（SCI4区）

25. Lu wang, Yuliang Liu Binbin Zhou* and Ming Zhong*   Synthesis and characterization of core-shell magnetic molecularly imprinted polymers for selective extraction of allocryptopine from the wastewater of Macleaya cordata (Willd) R. Br. Journal of Molecular Recognition，2020, 33，e2844.

26. Linlin Hou, Binbin Zhou*, Electrochemiluminescent Biosensors for the Detection of MicroRNAs: A Review, Int. J. Electrochem. Sci., 2019, 14, 2489-2508.

27. 周彬彬，张继红，王芳斌，汪霞丽，戴璇，郝远强*. 可视化分子探针的设计、合成及其对食品中氰化物的检测, 食品科学，2017, 12, 304-309.

28. Ning Xia, Binbin Zhou, Nanbing Huang, Mengsha Jiang, Jiebing Zhang, LinLiu*, Visual and fluorescent assays for selective detection of beta-amyloid  oligomers based on the inner filter effect of gold nanoparticles on the fluorescence of CdTe quantum dots, Biosens. Bioelectro., 2016, 85, 625–632.

29. Ming La, Lin Liu*, Binbin Zhou*, Nanomaterials-based fluorimetric methods for microRNAs detection, Materials, 2015, 8, 2809-2829.

30. Ning Xia, Lin Liu , Zhifang Sun*,  Binbin Zhou*, Nanocomposites of grapheme with ferrocene or hemin:Preparation and application in electrochemical sensing，Journal of Nanomaterials, 2015, 9, 1-9.

31. Sujuan Li*, Ning Xia, Baiqing Yuan, Weimin Du, Zhifang Sun, Binbin Zhou*, A novel DNA sensor using a sandwich format by electrochemical measurement of marker ion fluxes across nanoporous alumina membrane, Electrochimica Acta, 2015,159, 234-241.

32. Binbin Zhou, Zhifang Sun, Ding Li, Ting Zhang, Liu Deng and You-Nian Liu*, Platinum Nanostructure via a Self-assembly of Amyloid-like Peptide: a Novel Electrocatalyst for the Oxygen Reduction, Nanoscale., 2013, 5, 2669–2673.

33. Binbin Zhou (并列第一), Yuangqiang Hao, Liu Deng and You-Nian Liu*,Biosens. Bioelectro., Construction of highly ordered polyaniline nanowires and their applications in DNA sensing, Biosens. Bioelectro., 2014, 52, 422-426.

34. Binbin Zhou, Juan Li, Bi-Jun Feng, You-Nian Liu* and Feimeng Zhou*, Syntheses and in Vitro Antitumor  Activities of Ferrocene-conjugated Arg-Gly-Asp Peptides, J. Inorg. Biochem., 2012, 116, 19-25.

35. Binbin Zhou, Yuangqiang Hao, You-Nian Liu* and Feimeng Zhou*, Conversion of Natively Unstructured α-synuclein to it’s α-helixcal Conformation Singnificantly Attenuates Production of Reactive Oxygen Species, J. Inorg. Biochem., 2013, 118, 68-73.

36. Binbin Zhou, Chun-Lan Li, You-Nian Liu* and Juan Li, Ferrocene Tripeptide Gly-Pro-Arg Conjugates: Synthesis and Inhibitory Effects on Alzheimer’s Aβ_1–42 Fibrillogenesis and Aβ-induced Cytotoxicity in Vitro, Bioorg. Med. Chem., 2013, 21, 395-402.

授权专利：

1．周彬彬、王芳斌、张继红、戴璇、汪霞丽、康绍英, 一种基于多肽识别基团的荧光探针、其制备方法及其对铜离子与氰根离子的检测方法, 专利号：ZL20161005227.X。

2. 周彬彬、钟明、李凯龙、张继红，一种能同时抑制Aβ聚集和络合铜离子的纳米药物其制备、及应用方法，申请号：201911018462.5。

3. 李凯龙、周彬彬、杨滔，抗菌涂层剂及其制备方法和应用，专利号：ZL201910633945.X。

4. 周彬彬、盛兴欣、谢豪、钟明，一种基于分子印迹传感器的呋喃西林检测方法，专利号：ZL202211243482.4。

5. 周彬彬、盛兴欣、谢豪、李欣怡、钟明，基于铁氰化铜信号探针的分子印迹CuMOFs电化学传感器的构建方法及应用，专利号：ZL202310015119.5。

6. 周彬彬、谢豪、盛兴欣、钟明，基于石墨烯纳米带与金纳米粒子协同作用的电化学传感器的制备方法及应用，专利号：ZL202310004469.1。

个人简介

周彬彬，1984年12月出生，湖南平江人，教授，硕士生导师。2013年5月，于中南大学化学化工学院应用化学专业获博士学位。2009-2011年，在美国加州州立大学洛杉矶分校进行联合培养。主持省自然科学基金项目3项，主持省食药监局科研项目2项，主持省教育厅科研项目和教改项目各1项，主持横向课题4项；参与食品安全国家标准制修订项目3项，食品安全地方标准制定项目2项。以第一作者或通讯作者身份在Food Chemistry，Biosensors & Bioelectronics, Chemical Engineering Science, Food Chemistry: X, Microchemical Journal等杂志发表SCI、EI收录论文40余篇；申请国家发明专利9件，已授权6件。以主编和副主编身份编写教材2部。