化学化工学院硕士研究生导师
姓 名:刘宇2
学 科:有机合成
研究方向:有机合成方法学和药物合成化学
电话:13657309310
电子邮件:lyxtmj_613@163.com
个人和研究方向简介:
1985年生,男,博士,讲师。
刘宇老师多年来对C-H键官能团化和光催化反应开展了研究,提出了的C-H键官能团化的新方法,并将光催化方法应用到新的反应体系中。其研究成果为含环状骨架药物的合成提供了新途径和新思路,也为光催化的进一步开发和应用提供了重要依据。目前主持国家自然科学基金1项,湖南省教育厅重点项目1项,负责与中石化巴陵分公司横向合作项目1项(已结题)。
刘宇老师已经在Angewandte Chemie International Edition、Journal of the American Chemical Society、Chemical Science、Chemical Communication等国际高水平刊物上发表论文30余篇,其中第一作者和通迅作者10篇。
代表性论著:
(1) Yu Liu, Jia-Ling Zhang, Ren-Jie Song, Peng-Cheng Qian, and Jin-Heng Li*, Cascade Nitration/Cyclization of 1,7-Enynes with tBuONO and H2O: One-Pot Self-Assembly of Pyrrolo[4,3,2-de]quinolinones, Angewandte Chemie International Edition, 2014,53(34): 9017-9020
(2) Yu Liu, Jia-Ling Zhang, Ming-Bo Zhou, Ren-Jie Song, and Jin-Heng Li*, Copper-Catalyzed Cascade Cyclization of 1,7-Enynes with Aromatic Sulfonyl Chlorides toward Benzo[j]phenanthridin-6(5H)-ones, Chemical Communications, 2014, 50(92): 14412-14414
(3) Yu Liu, Ren-Jie Song and Jin-Heng Li*, Palladium-Catalyzed Dearomatizative [2+2+1] Carboannulation of 1,7-Enynes with Aryl Diazonium Salts and H2O: Facile Synthesis of Spirocyclohexadienone-Fused Cyclopenta[c]quinolin-4(5H)-ones, Chemical Communications, 10.1039/C7CC02830J. (Just accepted paper)
(4) Yu Liu*, Qiao-Lin Wang, Cong-Shan Zhou, Bi-Quan Xiong, Pan-Liang Zhang, Chang-an Yang and Ke-Wen Tang*, Metal-Free Oxidative C-C Bond Functionalization of Methylenecyclopropanes with Ethers Leading to 2-Substituted 3,4-dihydronaphthalenes. The Journal of Organic Chemistry, 10.1021/acs.joc.7b00970. (Just accepted paper)
(5) Yu Liu, Jia-Ling Zhang, Ren-Jie Song, and Jin-Heng Li*. Sulfur-Incorporation: Cu-Catalyzed Cascade Cyclization of 1,7-Enynes with Metal Sulfides Toward Thieno[3,4-c]quinolin-4(5H)-ones, Organic Letters, 2014, 16(22): 5838-5841
(6) Peng-Cheng Qian, Yu Liu*, Ren-Jie Song, Ming Hu, Xu-Heng Yang, Jian-Nan Xiang*, and Jin-Heng Li*, (Diacetoxyiodo)benzene-Mediated Oxygenation of Benzylic C(sp3)-H Bondswith N-Hydroxyamides at Room Temperature, European Journal of Organic Chemistry, 2015(8): 1680-1684
(7) Yu Liu*, Renjie Song, Jinheng Li*, The cycloaddition reaction using visible light photoredox catalysis, Science China Chemistry, 2016, 59(2): 161-170
(8) Yu Liu, Jia-Ling Zhang, Ren-Jie Song, and Jin-Heng Li*, 1,2-Alkylarylation of Activated Alkenes with Dual C-H Bonds of Arenes and Alkyl Halides Toward Polyhalo-Substituted Oxindoles, Organic Chemistry Frontiers, 2014, 1(11): 1289-1294
(9) Yu Liu, Jia-Ling Zhang, Ren-Jie Song, and Jin-Heng Li*, Visible-Light- Facilitated 5-exo-trig Cyclization of 1,6-Dienes with Alkyl Chlorides: Selective Scission of the C(sp3)-H Bond in Alkyl Chlorides, European Journal of Organic Chemistry, 2014(6): 1177-1181
(10) Yu Liu, Ren-Jie Song, and Jin-Heng Li*, Yb(OTf)3-Promoted ZnCl2-Catalyzed Conia-Ene Reaction of Linear β-Alkynic β-Ketoesters, Synthesis, 2010, 21, 3663-3669