化学化工学院硕士研究生导师
姓 名:向阳
学 科:分子遗传学
研究方向:生殖相关基因功能研究
电话/传真:0730-8640122
电子邮件:xiangyangbio@126.com
个人和研究方向简介:
1968年生,男,博士,教授,硕士生导师,十二五湖南省生物化学与分子生物学省重点建设学科带头人。主要从事基因工程、分子生物学、分子遗传学等教学和生殖及肿瘤基因功能研究工作。主持和参与国家及省部级科研项目8项:主持国家自科基金面上项目一项,国家外事办引智项目两项,湖南省教育厅重点课题一项,湖南省社科院项目一项;作为第二参与人参加了国家科技部“十一五”863重点课题一项,作为第一参与人参加国家自然科学基金项目一项和湖南省卫生厅一般项目一项。近年,发表省部级以上科研论文35篇,其中SCI收录科研论文15篇。出版专著两部。
1. 代表性论文:
Cloning, characterization and identification of Rcet1-v1 and Rcet1-v2, two novel splice variants of mouse Rcet1 related to Cres subgroup of family 2 cystatins. DNA sequence, 2008. 排名第1
2. Knocking down Wnt9a mRNA levels increases cellular proliferation. Mol Biol Rep. 2008. 排名第1
3. Cloning, Characterization and Primary Function Study of a Novel Gene, Cymg1, Related to Family 2 Cystatins, Acta Biochim Biophys Sin 2005. 排名第1
4. Identification of one mouse novel Rcet3 gene related to Cres subgroup of the family 2 cysyatins. Abstracts-Aspire:Optimizing infertility management in Asia, 2006. 排名1
5. Differential Expression of Wnts, β-catenin and E-cadherin in hEFs and Normal, Abnormal Karyotype hES Cells during Culture in vitro. Journal of Life Sciences. 2011. 通讯作者
6. The Role of Mouse Wnt9a in MA891 Breast Cancer Cell Proliferation. Journal of Life Sciences. 2011. 通讯作者
7. Preliminary Functional Study on Wnt9a Cloning from Human Embryonic Stem Cells. Journal of Life Sciences. 2011. 通讯作者
8. A novel chromosomal passenger taking in ES selfrenewal spermatogenes. Abstract-Aspire: Optimizing infertility management in Asia..2006. 排名第2
9. Molecular cloing and characterization of a novel human testis-spcific gene by use of digital differential display . Journal of genetics.2006. 排名第2
10. Molecular cloning and expression profile analysis of a novel mouse testis-specific expression gene mtIQ1. Mol Biol Rep.2009. 排名第2
11. Identification of a Novel Testis-Specific gene mtLR1 , Which Is Expressed at Specific Stages of Mouse Spermatogenesis. Biochemical and Biophysical Research Communications. 2005. 排名第2
12. Overexpression a novel zebra fish spermatogenesis-associated gene 17 (SPATA17) induces apoptosis in GC-1 cells. Mol Biol Rep. 2011. 排名第3
13. Molecular cloing and primary functional analysis of a novel human testis-specific gene. Acta Genetica Sinica..2005. 排名第3
14. Cloning and preliminary functional study of a novel stem cell-specific gene encoding a protein methyltransferase. Abstract-Aspire: Optimizing infertility management in Asia.2006. 排名第3
15. Molecular Cloning of a Novel Mouse Testis-specific Spermatogenic Cell Apoptosis Inhibitor Gene mTSARG7 as a Candidate Oncogene Acta Biochim Biophys Sin..2005. 排名第8
16. Tumor Progression of Culture-Adapted Human Embryonic Stem Cells During Long-Term Culture. GENES, CHROMOSOMES & CANCER..2008. 排名第11
代表性专著:
1. X染色体上的癌-睾抗原。
2. Y染色体上的癌-睾抗原。