导师简介

聂东宋教授

 

化学化工学院硕士研究生导师

 

:聂东宋

:遗传学

研究方向:生殖相关基因的克隆及功能研究、新型体外诊断试剂盒的开发

电话/传真0730-8640122

电子邮件ndz1997@126.com

个人和研究方向简介

聂东宋,男,196503月生,湖南理工学院教授,硕士生导师,湖南省高校生物学科带头人。现任化学化工学院副院长,湖南理工学院致公党支部主委。湖南省生物化学与分子生物学理事。            

聂东宋教授10多年来一直从事人类生殖域相关基因的克隆及功能研究,先后克隆8个人类睾丸特异表达新基因,并对其功能进行了研究,在该领域主持国家自然科学基金面上项目3项。同时对蛋白质的原核和真核表达、蛋白质的分离纯化也有一定研究,在丙型肝炎病毒的快速检测方面申请国家专利1项,主持了国家“863”重点项目1项。以第一作者或通讯作者学术论文30余篇,其中SCI论文10余篇。

代表性文章

1FISH is more sensitive than Southern analysis at identifying increased levels of cyclin D1 gene amplified in breast cancer cell lines Mol Biol Rep (2010) 37:3473–3480

2Overexpression a novel Zebra fish spermatogenesis associated gene 17 induces apoptosis in GC-1 cells Mol Biol Rep (2011) 383945-3952

3、丙型肝炎病毒多表位抗原的融合表达及抗原性分析中国现代医学杂志2010.202):209-213

4Molecular cloning and expression profile analysis of a novel mouse testis-specific expression gene mtIQ1 Mol Biol Rep (2009) 36:1203–1209

5Cloning and primarily function study of two novel putative N (5)-glutamine methyltransferase ( Hemk ) splice variants from mouse stem cellsMol Biol Rep (2009) 36:2221–2228

6Molecular cloning and characterization of a novel human testis-specific gene by use of digital differential display. J Genet.2006.85(1)57-62

7Sequencing of Phosphopeptide using Post-Decay Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Asian Journal of Chemistry (2011), 238):3339-3343

8Clonging and Expression of a Neurotoxin Peptide Gene from Chinese Bird SpiderCh in J Appl Environ B iol2006125):651-655

9Three ferritin subunit analogs in Chinese giant salamander (Andrias davidianus) and their response to microbial stimulationMolecular Immunology2015,67:642-651;

10Cloning and Characterization of Immune Molecule CD9 Homolog in Chinese Giant Salamander ( Andrias davidianus)Chinese Journal of Biochemistry and Molecular Biology.2015, 31(4):397-407

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